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PrenatalSAFE NIPT

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PrenatalSAFE NIPT: Comprehensive Prenatal Genetic Screening for Peace of Mind

Non-invasive prenatal tests (NIPT) like PrenatalSafe have been shown to perform better than traditional prenatal screening methods, and they avoid the risk of miscarriage associated with invasive diagnostic procedures such as amniocentesis and chorionic villus sampling (CVS). According to the  International Society for Prenatal Diagnosis (ISPD) and American College of Medical Genetics and Genomics (ACMG) support offering NIPT as a first-line screen., non-invasive prenatal testing  is appropriate as a Primary Screening Test for pregnant women of all ages. Down Syndrome and certain other chromosomal conditions occur more frequently in babies born to mothers over 35 years old. Other conditions for which NIPT  screens – such as microdeletion syndromes – occur with the same frequency in babies, regardless of the mother’s age. The PrenatalSAFE  non-invasive prenatal test screens for aneuploidies PrenatalSAFE is a test indicated for patients with: • Maternal age-related risks (≥35 years) • Ultrasound finding(s) suggestive of an aneuploidy • Personal or family history of chromosomal aneuploidy • One of the partners with a balanced chromosome 13 or 21 Robertson translocation • Low-risk pregnancies To secure your appointment at Miracle Inside Diagnostic Scan Centre, the following payments are required:
  • Deposit: A non-refundable deposit of £30.
  • Phlebotomy Charges: An additional fee of £25 is charged for phlebotomy services and DHL courier service to timely deliver the blood to the laboratory.
These payments must be made when booking to confirm your appointment. The remaining balance for your services can be paid through our website after your appointment. This ensures a smooth and efficient process for both our staff and patients. For any questions or assistance regarding payment, don't hesitate to get in touch with our customer service team at 01134608760
  • PrenatalSAFE 3 without Scan - £ 300
  • PrenatalSAFE 3  with Scan  ( a Quick Viability Scan is offered till 15 weeks of Pregnancy ) -  £ 350
Is done for the screening of aneuploidies such as Downs syndrome, Edwards syndrome, Patau syndrome with a  Dating Scan Included
  • 15 -minute Appointment with a Qualified Health Professional
  • 1 sample of blood will be taken from the arm of the mother
  • 10-week prenatal genetic test (singleton pregnancy only)
  • If Fetal DNA sex Aneuploidies of Baby needed please  upgrade to Prenatal safe 5
  • Results of test  will be emailed to the client
For further information, please see the test provider’s Technical Analysis Report by clicking here. Please click here to book the NIPT Test along with an Ultrasound scan appointment Book Your Prenatalsafe NIPT Blood test  . Today

Online Booking System

  • PrenatalSAFE 5 without Scan - £ 350
  • PrenatalSAFE 5  with Scan ( a Quick Viability Scan is offered till 15 weeks of Pregnancy ) -  £ 400
Screens for aneuploidies such as Downs syndrome, Edwards syndrome, Patau syndrome, and also the screening of aneuploidies such as Turner Syndrome, Jacobs syndrome and Klinefelter Syndromes, plus Trisomy X with a  Dating scan
  • 15 -minute Appointment with a Qualified Health Professional
  • 1 sample of blood will be taken from the arm of the mother with this package is Included DNA sexing of Baby (singleton pregnancy only)
  • Results of test will be emailed to the client
  • This test includes the determination of fetal sex. a prenatal genetic test (singleton pregnancy only)
For further information, please see the test provider’s Technical Analysis Report by clicking here. We provide a same-day blood result service for some blood tests (Monday – Friday, excluding Bank Holidays). A £ 25  for Phlebotomy + Courier charge will be applied for all Bloods .
Please inform us at the time of booking if you require same-day results.
  • PrenatalSAFE 5 plus without Scan - £ 450
  • PrenatalSAFE 5 plus  with Scan ( a Quick Viability Scan is offered till 15 weeks of Pregnancy ) -  £ 500
Screens for aneuploidies such as Downs syndrome, Edwards syndrome, Patau syndrome and also the screening of aneuploidies such as Turner Syndrome, Jacobs syndrome and Klinefelter Syndromes, plus Trisomy X , Panel of 6 microdeletions (+Trisomies 9 and 16 ) with a option of  Dating scan
  • 15 -minute Appointment with a Qualified Health Professional
  • 1 sample of blood will be taken from the arm of the mother with this package is Included DNA sexing of Baby (singleton pregnancy only)
  • 6-panel microdeletions - DiGeorge syndrome, - 1p36 deletion syndrome, - Angelman Syndrome, - Prader-Willi syndrome, - Cri du Chat syndrome - Wolf-Hirschhorn Syndrome.
  • Results of test emailed to the client
  • This test includes the determination of fetal sex. a prenatal genetic test (singleton pregnancy only)
For further information, please see the test provider’s Technical Analysis Report by clicking here.
  • PrenatalSAFE Karyo without ultrasound  - £600
  • PrenatalSAFE Karyo with Ultrasound  ( a Quick Viability Scan is offered till 15 weeks of Pregnancy ) - £650
Genome-wide NIPT that provides karyotype-level insight and screens all the conditions included in PrenatalSafe 5, plus less frequent chromosomal aneuploidies such as Trisomy’s 1 to 22. plus less frequent chromosomal aneuploidies such as Trisomy’s 1 to 22 with a  Dating scan
  • Maternal age-related risks (≥35 years)
  • Ultrasound finding(s) suggestive of an aneuploidy
  • Personal or family history of chromosomal aneuploidy
  • One of the partners with a balanced chromosome 13 or 21 Robertson translocation
  • Low-risk pregnancies
For further information, click HERE or the image to download a copy of the brochure. For further information, please see the test provider’s Technical Analysis Report by clicking here.
  • PrenatalSAFE KARYO PLUS with Ultrasound   - £650
  • PrenatalSAFE Karyo with Ultrasound ( a Quick Viability Scan is offered till 15 weeks of Pregnancy ) - £700
Karyo Plus Genome-wide NIPT that provides karyotype-level insight + panel 9 Microdeletions**Test Analyses every chromosome in the genome as well as 9 clinically significant microdeletion syndromes DiGeorge, Cri-du-chat, Prader-Willi, Angel man, 1p36 deletion, Wolf-Hirschhom, Jacobsen, Langer-Giedion, Smith-Magenis Syndromes with a Dating scan
  • 9-panel microdeletions:- DiGeorge syndrome, - 1p36 deletion syndrome, - Angelman Syndrome, - Prader-Willi syndrome, - Cri du Chat syndrome - Wolf-Hirschhorn Syndrome. - Langer-Gleidon syndrome, - Jacobsen syndrome and - Smith-Magenis syndrome
  • Personal or family history of chromosomal aneuploidy
  • One of the partners with a balanced chromosome 13 or 21 Robertson translocation
  • Low-risk pregnancies
  • For further information, Click HERE or the image to download a copy of the brochure.
Please see the test provider’s Technical Analysis Report by clicking here for further information.
  • PrenatalSAFE® ( Karyo + GeneSAFE™)  COMPLETE with Ultrasound – £ 1200
  • PrenatalSAFE® ( Karyo + GeneSAFE™)  COMPLETE with Ultrasound Scan  - £1250
This test screens for 5 common inherited recessive genetic disorders, such as Cystic Fibrosis, Beta-Thalassemia, Sickle cell anaemia, Deafness autosomal recessive type 1a and 1b. Allows detection of common inherited disorders within the foetus. Genes screened: CFTR, CX26 (GJB2), CX30 (GJB6), HBB . For further information, Click HERE or the image to download a copy of the brochure. For further information, please see the test provider’s Technical Analysis Report by  clicking here
  • PrenatalSAFE® ( Karyo + GeneSAFE™)  COMPLETE Plus  with Ultrasound – £ 1300
  • PrenatalSAFE® ( Karyo + GeneSAFE™)  COMPLETE with Ultrasound Scan  - £1350
This test screens for 44 severe genetic disorders due to de novo mutations (a gene mutation that is not inherited) in 25 genes. Many disorders screened with GeneSafe De Novo are not typically associated with abnormal prenatal ultrasound findings (especially in the first trimester), or may not be evident until the late second/third trimester, when confirmatory invasive testing can pose a risk of pre-term birth, or the baby’s health after delivery. Genes screened: ASXL1, BRAF, CBL, CHD7, COL1A1, COL1A2 , COL2A1, FGFR2, FGFR3, HDAC8, JAG1, KRAS, MAP2K1, MAP2K2, MECP2, NIPBL, NRAS, NSD1, PTPN11, RAF1, RIT1, SETBP1, SHOC2, SIX3, SOS1 For further information, click HERE or the image to download a copy of the brochure. For further information, please see the test provider’s Technical Analysis Report by  clicking here
  • PrenatalSafe Facilitates Early Diagnosis Of Single-Gene Disorders. The First Non-Invasive Prenatal Test that Screens Multiple Genes For Mutations Causing Severe Genetic Disorders In The Foetus.
  • Prenatalsafe works as a complementary screen to traditional and genome-wide NIPT PrenatalSafe KARYO. GeneSafe screens for several life-altering genetic disorders that are not screened with current NIPT technology, allowing for a more complete picture of the risk of a pregnancy being affected by a genetic disorder.
  • Clinical Performance Report for PrenatalSAFE®  NIPT
  • To contact us for more information, to know about these blood tests, call  📞 01138301371  to speak with the Healthcare Professional.
What is diagnosed? PrenatalSAFEis a Non-Invasive Prenatal test that detects common chromosomal aneuploidies on chromosome 21 (Down Syndrome), chromosome 18 (Edwards Syndrome) and chromosome 13 (Patau Syndrome) and those of the X and Y sexual chromosomes, such as Turner Syndrome, Klinefelter Syndrome and Jacobs Syndrome, by analysing fetal DNA in circulation. PrenatalSAFE offers a further second level of testing that diagnoses structural chromosomal alterations, among which a few common microdeletion syndromes (DiGeorge Syndrome, Cri-du-chat Syndrome, Prader-Willi Syndrome, Angelman Syndrome, 1p36 deletion Syndrome, Wolf-Hirschhorn Syndrome), and Trisomy 9 and 16. Prenatal SAFE can find chromosomal aneuploidies even on low quantities of fetal DNA (2%), in comparison to other tests that require >4% of fetal DNA. What do about my Regular NHS 12-week scan and NT measurements scans? If you are having an NIPT Test or you have got negative or Low-risk results on the Non-Invasive Prenatal  Test, you should still attend and not miss your regular 12-week NHS  scan and the NT measurements. For further information, please see the test provider’s Technical Analysis Report by clicking here. Genetic counselling is available to all Prenatal SAFE clients on request. Contact us about this service, and we will put you in touch with someone who is trained to talk you through your results when there are Positive Outcomes. What do about my Regular NHS 12-week scan and NT measurements scans? If you are having an NIPT Test or you have got negative or Low-risk results on the Non-Invasive Prenatal  Test, you should still attend and not miss your regular 12-week NHS  scan and the NT measurements. What if the sample fails? Statistically, there is a 3 to 4% failure rate because there is not enough cell-free DNA in the blood sample to analyse. In this event, a new sample will need to be taken again at no extra cost. What if I have a high BMI? The relative proportion of cell-free fetal DNA is reduced in women with a high BMI as they have more of their own cell-free DNA circulating in their blood. This may increase the chance of getting an inconclusive result.

PrenataSafe NIPT Test – Frequently Asked Questions (FAQs)

1. What is the PrenataSafe NIPT test?

The PrenataSafe Non‑Invasive Prenatal Test (NIPT) is a blood test that screens for common chromosomal conditions in an unborn baby by analysing fetal DNA circulating in the mother’s blood. It is highly accurate and safe because it does not involve invasive procedures.

2. How does the PrenataSafe NIPT test work?

PrenataSafe analyses tiny fragments of fetal DNA that naturally cross into the mother’s bloodstream during pregnancy. A sample of the mother’s blood is collected and sent to the lab, where advanced genetic technology checks for patterns associated with chromosomal abnormalities.

3. When can the PrenataSafe test be done?

The PrenataSafe test can typically be performed from 10 weeks of pregnancy onward. It is designed to be used early in pregnancy to give you actionable information as soon as possible.

4. What conditions can PrenataSafe detect?

PrenataSafe can screen for several chromosomal conditions, including:

  • Trisomy 21 (Down syndrome)

  • Trisomy 18 (Edwards syndrome)

  • Trisomy 13 (Patau syndrome)
    It may also report on sex chromosome differences and other genetic findings, depending on the specific panel ordered.

5. Is the PrenataSafe NIPT test safe?

Yes. PrenataSafe is non‑invasive and poses no risk to the pregnancy, because it uses a simple blood draw from the mother. Unlike invasive tests such as amniocentesis or CVS, it does not increase the risk of miscarriage.

6. How accurate is the PrenataSafe test?

PrenataSafe is highly accurate at screening for the common trisomies it tests for, with detection rates often above 99% for Down syndrome. However, it is still a screening test, not a diagnostic test, which means it estimates risk rather than confirming a genetic condition.

7. Do I need a referral from my doctor?

In most cases, you do not need a doctor’s referral to book PrenataSafe through private services like Miracle Inside. However, talking to your maternity care team or GP before testing is encouraged to understand how it fits into your overall prenatal care.

8. How long does it take to get results?

Results are usually available within 7–10 working days after the laboratory receives your sample. You will receive a written report and, if needed, discussion with a healthcare professional.

9. What do the results mean?

  • Low risk: The test did not detect a high risk for the screened conditions. Routine care continues.

  • High risk: The test suggests an increased likelihood of a chromosomal condition. Your care provider may recommend diagnostic testing (e.g., amniocentesis or CVS) to confirm.

10. Can PrenataSafe tell the baby’s sex?

Depending on the panel and preferences stated at booking, the test can often provide information about the baby’s chromosomal sex. This is optional and should be requested when booking.

11. Is the test covered by insurance?

Private PrenataSafe testing is usually self‑funded, and costs vary by provider. Check with your insurer or clinic for coverage details.

12. What should I do if my test showsa  high risk?

A high‑risk result does not mean your baby definitely has the condition. It means further testing is recommended. Your healthcare provider may suggest diagnostic procedures such as amniocentesis or chorionic villus sampling (CVS) for confirmation and to guide care.

13. Can multiple pregnancies (twins, triplets) be tested?

Yes, PrenataSafe can often screen multiple pregnancies, though interpretation may be more complex. Always discuss this at booking so the lab can process the sample appropriately.

14. Is there anything that can affect the accuracy of the test?

Several factors can influence results, including:

  • Low fetal fraction (amount of fetal DNA in the sample)
  • High maternal weight
  • Recent blood transfusion or organ transplant
  • Multiple pregnancy
    If the test is inconclusive, a repeat blood sample may be requested.

15. How do I book the PrenataSafe NIPT test at Miracle Inside?

You can book by calling 01138301371 , scheduling online, or speaking with a healthcare professional at our Leeds clinics. A booking deposit is required, and staff will guide you through preparation and the next steps.

Why PrenataSafe Matters

PrenataSafe offers expectant parents early insight into genetic risk with a simple, safe blood test. Early information can help you plan medical care, make informed decisions, and approach pregnancy with confidence and clarity.

We will require details of your GP / Health Care Professional, which may be requested before or at the time of the scan. This scan requires access to the area of interest; it is recommended to wear loose clothing to facilitate this process. Blood results require interpretation, and all results should be shared with your regular healthcare professional / GP, / Fertility specialist. All of our first-line ultrasound scans & health Blood tests are optional. You must be at least 16 years old, and you should have no existing medical condition or treatment pending that relates to the scan/blood test you are booking. If you are in any doubt about having any type of test, you should consult your GP. The Geneticist, in the context of Genetic Counselling, will explain in detail the test result and advise to confirm the result by invasive prenatal diagnosis. is provided as part of this Blood test Service. The customer's regular Healthcare professional / GP / Fertility specialist is responsible for ensuring appropriate counselling is provided to the patient. Please note: A £50 non-refundable deposit is payable upon booking. Should you wish to alter your appointment time, please give the boutique a minimum of 48 hours' notice. Please refer to the individual boutiques’ opening times. Book Your Prentalsafe  NIPT Blood test  . Today Here are some additional resources that may be useful: - Antenatal Results and Choices (ARC): This is a national charity that provides non-directive support and information to parents before, during, and after antenatal screening. You can visit their website at www.arc-uk.org or call their helpline at 0845 077 2290 or 0207 713 7486. The helpline is open from Monday to Friday, 10 am to 5:30 pm. - Down's Syndrome Association: This association provides support for people with Down's syndrome and their families. You can visit their website at www.downs-syndrome.org.uk or call them at 0333 1212 300. They are open from Monday to Friday, 10 am to 4 pm. - Support Organisation for Trisomy 13/18 (SOFT): This organisation provides information and support for families affected by Trisomy 13/18. You can visit their website at www.soft.org.uk.
We offer a wide range of blood tests, but the list below is not comprehensive. If you can’t find what you need or need more information, please feel free to contact us at 01138301371 and speak to one of our healthcare professionals. We’ll be more than happy to help you out.
  • We provide a same-day blood result service for some blood tests (Monday –  Saturday, excluding Bank Holidays).
  • A £ 35 fee for Phlebotomy + Courier charge will be applied for all Bloods.
Please inform us at the time of booking if you require same-day results.
The Appropriate cancellation charge will apply as shown below.
  • Amendments: 72 hrs ( 3 days Notice )
  • Bookings made on the same day or 1 to 3 days before your appointment cannot be amended.
  • Refund Applicable: 14 Days or more: Full refund
  • Between 10 and 14 days: £30 non-refundable deposit balance paid will be refunded
  • Between 1 and 9 days: No refund will be given
  • Failure to attend: No refund will be given
  • Rescheduled Appointments are not eligible for Cancellation or Refunds.
At Miracle Inside Diagnostic Scan Centre, we firmly believe that knowledge is the cornerstone of good health. Our dedicated team is committed to supporting you on your unique health journey, offering expertise, compassion, and confidentiality every step of the way. To Get Your appointment booked, please CLICK HERE Book an appointment with GODSON JOHNSON using Setmore
Book Now £300